Antibodies against a Surface Protein of Streptococcus pyogenes Promote a Pathological Inflammatory Response

Streptococcal toxic shock syndrome (STSS) caused by Streptococcus pyogenes is a clinical condition with a high mortality rate despite modern intensive care. A key feature of STSS is excessive plasma leakage leading to hypovolemic hypotension, disturbed microcirculation and multiorgan failure. Previo...

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Main Authors: Kahn, Fredrik, Mörgelin, Matthias, Shannon, Oonagh, Norrby-Teglund, Anna, Herwald, Heiko, Olin, Anders I., Björck, Lars
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522270/
https://ncbi.nlm.nih.gov/pubmed/18787689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000149
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