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FKBP12 deficiency reduces strength deficits after eccentric contraction-induced muscle injury
Strength deficits associated with eccentric contraction-induced muscle injury stem, in part, from excitation-contraction uncoupling. FKBP12 is a 12-kDa binding protein known to bind to the skeletal muscle sarcoplasmic reticulum Ca(2+) release channel [ryanodine receptor (RyR1)] and plays an importan...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519949/ https://ncbi.nlm.nih.gov/pubmed/18511525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01145.2007 |
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