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Cyclin T1-Dependent Genes in Activated CD4(+) T and Macrophage Cell Lines Appear Enriched in HIV-1 Co-Factors
HIV-1 is dependent upon cellular co-factors to mediate its replication cycle in CD4(+) T cells and macrophages, the two major cell types infected by the virus in vivo. One critical co-factor is Cyclin T1, a subunit of a general RNA polymerase II elongation factor known as P-TEFb. Cyclin T1 is target...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519787/ https://ncbi.nlm.nih.gov/pubmed/18773076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003146 |
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