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Regulation of Cyclin T1 and HIV-1 Replication by MicroRNAs in Resting CD4(+) T Lymphocytes

The replication of integrated human immunodeficiency virus type 1 (HIV-1) is dependent on the cellular cofactor cyclin T1, which binds the viral Tat protein and activates the RNA polymerase II transcription of the integrated provirus. The activation of resting CD4(+) T cells upregulates cyclin T1 pr...

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Autors principals: Chiang, Karen, Sung, Tzu-Ling, Rice, Andrew P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302325/
https://ncbi.nlm.nih.gov/pubmed/22205749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05065-11
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