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Regulation of Cyclin T1 and HIV-1 Replication by MicroRNAs in Resting CD4(+) T Lymphocytes
The replication of integrated human immunodeficiency virus type 1 (HIV-1) is dependent on the cellular cofactor cyclin T1, which binds the viral Tat protein and activates the RNA polymerase II transcription of the integrated provirus. The activation of resting CD4(+) T cells upregulates cyclin T1 pr...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302325/ https://ncbi.nlm.nih.gov/pubmed/22205749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05065-11 |
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