Llwytho...

Proteome-wide Profiling of Isoniazid Targets in Mycobacterium tuberculosis

Isoniazid (INH) is an essential drug used to treat tuberculosis. The mycobactericidal agents are INH adducts (INH-NAD(P)) of the pyridine nucleotide coenzymes, which are generated in vivo after INH activation, and which bind to, and inhibit, essential enzymes. The NADH-dependent enoyl-ACP reductase...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Argyrou, Argyrides, Jin, Lianji, Siconilfi-Baez, Linda, Angeletti, Ruth H., Blanchard, John S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519606/
https://ncbi.nlm.nih.gov/pubmed/17115689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061874m
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