In Vivo Emergence of Vicriviroc Resistance in a Human Immunodeficiency Virus Type 1 Subtype C-Infected Subject

Little is known about the in vivo development of resistance to human immunodeficiency virus type 1 (HIV-1) CCR5 antagonists. We studied 29 subjects with virologic failure from a phase IIb study of the CCR5 antagonist vicriviroc (VCV) and identified one individual with HIV-1 subtype C who developed V...

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Detalhes bibliográficos
Main Authors: Tsibris, Athe M. N., Sagar, Manish, Gulick, Roy M., Su, Zhaohui, Hughes, Michael, Greaves, Wayne, Subramanian, Mani, Flexner, Charles, Giguel, Françoise, Leopold, Kay E., Coakley, Eoin, Kuritzkes, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519584/
https://ncbi.nlm.nih.gov/pubmed/18495779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00444-08
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