Impaired Naive and Memory B-Cell Responsiveness to TLR9 Stimulation in Human Immunodeficiency Virus Infection

Toll-like receptor 9 (TLR9) agonists such as unmethylated bacterial CpG DNAs activate B lymphocytes directly, potentially influencing their function and homeostasis. To assess B-cell responsiveness to TLR9 agonists in human immunodeficiency virus (HIV) disease, we examined the ability of naive and m...

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Main Authors: Jiang, Wei, Lederman, Michael M., Mohner, Richard J., Rodriguez, Benigno, Nedrich, Todd M., Harding, Clifford V., Sieg, Scott F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519583/
https://ncbi.nlm.nih.gov/pubmed/18524824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00660-08
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