Functional Characterization of the Cleavage Specificity of the Sapovirus Chymotrypsin-Like Protease

Sapovirus is a positive-stranded RNA virus with a translational strategy based on processing of a polyprotein precursor by a chymotrypsin-like protease. So far, the molecular mechanisms regulating cleavage specificity of the viral protease are poorly understood. In this study, the catalytic activiti...

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Bibliografiska uppgifter
Huvudupphovsmän: Robel, Ivonne, Gebhardt, Julia, Mesters, Jeroen R., Gorbalenya, Alexander, Coutard, Bruno, Canard, Bruno, Hilgenfeld, Rolf, Rohayem, Jacques
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2008
Ämnen:
Genome Replication and Regulation of Viral Gene Expression
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519560/
https://ncbi.nlm.nih.gov/pubmed/18550673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00693-08
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