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vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis

Appropriate cell-cell signaling is crucial for proper tissue homeostasis. Protein sorting of cell surface receptors at the early endosome is important for both the delivery of the signal and the inactivation of the receptor, and its alteration can cause malignancies including cancer. In a genetic sc...

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Autori principali: Herz, Hans-Martin, Chen, Zhihong, Scherr, Heather, Lackey, Melinda, Bolduc, Clare, Bergmann, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519036/
https://ncbi.nlm.nih.gov/pubmed/16611691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02356
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