Biologic and genetic characterization of the novel amyloidogenic lambda light chain–secreting human cell lines, ALMC-1 and ALMC-2

Primary systemic amyloidosis (AL) is a rare monoclonal plasma cell (PC) disorder characterized by the deposition of misfolded immunoglobulin (Ig) light chains (LC) in vital organs throughout the body. To our knowledge, no cell lines have ever been established from AL patients. Here we describe the e...

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Detalhes bibliográficos
Main Authors: Arendt, Bonnie K., Ramirez-Alvarado, Marina, Sikkink, Laura A., Keats, Jonathan J., Ahmann, Gregory J., Dispenzieri, Angela, Fonseca, Rafael, Ketterling, Rhett P., Knudson, Ryan A., Mulvihill, Erin M., Tschumper, Renee C., Wu, Xiaosheng, Zeldenrust, Steven R., Jelinek, Diane F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518895/
https://ncbi.nlm.nih.gov/pubmed/18567838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-143040
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