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Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development
Rac GTPases have been implicated in the regulation of diverse functions in various blood cell lineages, but their role in T-cell development is not well understood. We have carried out conditional gene targeting to achieve hematopoietic stem cell (HSC)– or T-cell lineage–specific deletion of Rac1 or...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518885/ https://ncbi.nlm.nih.gov/pubmed/18579797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-132068 |
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