SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34

Salmonella colonizes a vacuolar niche in host cells during infection. Maturation of the Salmonella-containing vacuole (SCV) involves the formation of phosphatidylinositol 3-phosphate (PI(3)P) on its outer leaflet. SopB, a bacterial virulence factor with phosphoinositide phosphatase activity, was pro...

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Detalhes bibliográficos
Main Authors: Mallo, Gustavo V., Espina, Marianela, Smith, Adam C., Terebiznik, Mauricio R., Alemán, Ainel, Finlay, B. Brett, Rameh, Lucia E., Grinstein, Sergio, Brumell, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518712/
https://ncbi.nlm.nih.gov/pubmed/18725540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804131
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