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Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied

When the spindle assembly checkpoint (SAC) cannot be satisfied, cells exit mitosis via mitotic slippage. In microtubule (MT) poisons, slippage requires cyclin B proteolysis, and it appears to be accelerated in drug concentrations that allow some MT assembly. To determine if MTs accelerate slippage,...

詳細記述

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書誌詳細
主要な著者: Brito, Daniela A., Yang, Zhenye, Rieder, Conly L.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518701/
https://ncbi.nlm.nih.gov/pubmed/18710927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805072
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