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Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied

When the spindle assembly checkpoint (SAC) cannot be satisfied, cells exit mitosis via mitotic slippage. In microtubule (MT) poisons, slippage requires cyclin B proteolysis, and it appears to be accelerated in drug concentrations that allow some MT assembly. To determine if MTs accelerate slippage,...

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Bibliografski detalji
Glavni autori: Brito, Daniela A., Yang, Zhenye, Rieder, Conly L.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518701/
https://ncbi.nlm.nih.gov/pubmed/18710927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805072
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