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Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied
When the spindle assembly checkpoint (SAC) cannot be satisfied, cells exit mitosis via mitotic slippage. In microtubule (MT) poisons, slippage requires cyclin B proteolysis, and it appears to be accelerated in drug concentrations that allow some MT assembly. To determine if MTs accelerate slippage,...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518701/ https://ncbi.nlm.nih.gov/pubmed/18710927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805072 |
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