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Distinct functions of the major Fgf8 spliceform, Fgf8b, before and during mouse gastrulation
The vertebrate Fgf8 gene produces multiple protein isoforms by alternative splicing. Two evolutionarily conserved spliceforms, Fgf8a and Fgf8b, exhibit distinct bioactivities, with Fgf8b having a more potent inductive activity due to higher affinity for Fgf receptors. To investigate the in vivo requ...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518685/ https://ncbi.nlm.nih.gov/pubmed/17507393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.004929 |
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