Increase in Endoplasmic Reticulum Stress–Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals

OBJECTIVE—To examine fat biopsy samples from lean insulin-sensitive and obese insulin-resistant nondiabetic individuals for evidence of endoplasmic reticulum (ER) stress. RESEARCH DESIGN AND METHODS—Subcutaneous fat biopsies were obtained from the upper thighs of six lean and six obese nondiabetic s...

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Hlavní autoři: Boden, Guenther, Duan, Xunbao, Homko, Carol, Molina, Ezequiel J., Song, WeiWei, Perez, Oscar, Cheung, Peter, Merali, Salim
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2008
Témata:
Pathophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518495/
https://ncbi.nlm.nih.gov/pubmed/18567819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0604
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