Intracerebroventricular Administration of Neuropeptide Y Induces Hepatic Insulin Resistance via Sympathetic Innervation

OBJECTIVE—We recently showed that intracerebroventricular infusion of neuropeptide Y (NPY) hampers inhibition of endogenous glucose production (EGP) by insulin in mice. The downstream mechanisms responsible for these effects of NPY remain to be elucidated. Therefore, the aim of this study was to est...

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Main Authors: van den Hoek, Anita M., van Heijningen, Caroline, Schröder-van der Elst, Janny P., Ouwens, D. Margriet, Havekes, Louis M., Romijn, Johannes A., Kalsbeek, Andries, Pijl, Hanno
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2008
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518481/
https://ncbi.nlm.nih.gov/pubmed/18544708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1658
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