Intracerebroventricular Administration of Neuropeptide Y Induces Hepatic Insulin Resistance via Sympathetic Innervation

OBJECTIVE—We recently showed that intracerebroventricular infusion of neuropeptide Y (NPY) hampers inhibition of endogenous glucose production (EGP) by insulin in mice. The downstream mechanisms responsible for these effects of NPY remain to be elucidated. Therefore, the aim of this study was to est...

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Bibliografski detalji
Glavni autori: van den Hoek, Anita M., van Heijningen, Caroline, Schröder-van der Elst, Janny P., Ouwens, D. Margriet, Havekes, Louis M., Romijn, Johannes A., Kalsbeek, Andries, Pijl, Hanno
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2008
Teme:
Metabolism
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518481/
https://ncbi.nlm.nih.gov/pubmed/18544708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1658
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