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Physiological significance of high and low affinity agonist binding to neuronal and recombinant AMPA receptors
Radioligand binding studies have shown that AMPA receptors exist in two variants that differ about twentyfold in their binding affinities, with brain receptors being mainly of the low-affinity type and recombinantly expressed receptors having almost exclusively high affinity. However, the physiologi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518457/ https://ncbi.nlm.nih.gov/pubmed/18403051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2008.02.009 |
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