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Physiological significance of high and low affinity agonist binding to neuronal and recombinant AMPA receptors

Radioligand binding studies have shown that AMPA receptors exist in two variants that differ about twentyfold in their binding affinities, with brain receptors being mainly of the low-affinity type and recombinantly expressed receptors having almost exclusively high affinity. However, the physiologi...

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Bibliografiske detaljer
Main Authors: Kessler, Markus, Suzuki, Erika, Montgomery, Kyle, Arai, Amy C.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518457/
https://ncbi.nlm.nih.gov/pubmed/18403051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2008.02.009
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