IHG-1 Amplifies TGF-β1 Signaling and Is Increased in Renal Fibrosis

Induced in high glucose-1 (IHG-1) is an evolutionarily conserved gene transcript upregulated by high extracellular glucose concentrations, but its function is unknown. Here, it is reported that the abundance of IHG-1 mRNA is nearly 10-fold higher in microdissected, tubule-rich renal biopsies from pa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Murphy, Madeline, Docherty, Neil G., Griffin, Brenda, Howlin, Jillian, McArdle, Emmett, McMahon, Ruth, Schmid, Holger, Kretzler, Matthias, Droguett, Alejandra, Mezzano, Sergio, Brady, Hugh R., Furlong, Fiona, Godson, Catherine, Martin, Finian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2008
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518434/
https://ncbi.nlm.nih.gov/pubmed/18508967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007101080
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