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Organization of mammary epithelial cells into 3D acinar structures requires glucocorticoid and JNK signaling

Mammary epithelial cells cultured on a concentrated laminin-rich extracellular matrix formed 3D acinar structures that matured to polarized monolayers surrounding a lumen. In the absence of glucocorticoids mature acinus formation failed and the expression of an acinus-associated, activator protein 1...

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Main Authors: Murtagh, Janice, McArdle, Emmett, Gilligan, Emer, Thornton, Laura, Furlong, Fiona, Martin, Finian
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172147/
https://ncbi.nlm.nih.gov/pubmed/15226308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403020
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