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Intracellular Mg(2+) is a voltage-dependent pore blocker of HCN channels
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are activated by membrane hyperpolarization that creates time-dependent, inward rectifying currents, gated by the movement of the intrinsic voltage sensor S4. However, inward rectification of the HCN currents is not only observed in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518427/ https://ncbi.nlm.nih.gov/pubmed/18579800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00154.2008 |
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