A New Luminescence Assay for Autoantibodies to Mammalian Cell–Prepared Insulinoma-Associated Protein 2

OBJECTIVE—Insulinoma-associated protein 2 (IA-2) is a major autoantigen in type 1 diabetes, and IA-2 autoantibodies are routinely detected by a liquid-phase radioimmunoprecipitation assay. The present experiments were initiated to develop a new assay that does not require the use of radioisotopes or...

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Detalhes bibliográficos
Main Authors: Burbelo, Peter D., Hirai, Hiroki, Leahy, Hannah, Lernmark, Ake, Ivarsson, Sten A., Iadarola, Michael J., Louis Notkins, Abner
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2008
Assuntos:
Emerging Treatments and Technologies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518352/
https://ncbi.nlm.nih.gov/pubmed/18535195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc08-0286
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