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Group II Intron-Based Gene Targeting Reactions in Eukaryotes

BACKGROUND: Mobile group II introns insert site-specifically into DNA target sites by a mechanism termed retrohoming in which the excised intron RNA reverse splices into a DNA strand and is reverse transcribed by the intron-encoded protein. Retrohoming is mediated by a ribonucleoprotein particle tha...

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Detalhes bibliográficos
Main Authors: Mastroianni, Marta, Watanabe, Kazuo, White, Travis B., Zhuang, Fanglei, Vernon, Jamie, Matsuura, Manabu, Wallingford, John, Lambowitz, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518211/
https://ncbi.nlm.nih.gov/pubmed/18769669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003121
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