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Rh(I)-Catalyzed Alkylation of Quinolines and Pyridines via C-H Bond Activation
The scope of heterocycle ortho-alkylation has been dramatically expanded to include pharmaceutically important pyridines and quinolines, which contain only a single nitrogen. The reactions, which are conducted at a high concentration (0.8 M), can be performed with catalyst loadings as low as 1% Rh....
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518126/ https://ncbi.nlm.nih.gov/pubmed/17411050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja070388z |
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