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Rh(I)-Catalyzed Alkylation of Quinolines and Pyridines via C-H Bond Activation

The scope of heterocycle ortho-alkylation has been dramatically expanded to include pharmaceutically important pyridines and quinolines, which contain only a single nitrogen. The reactions, which are conducted at a high concentration (0.8 M), can be performed with catalyst loadings as low as 1% Rh....

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Библиографические подробности
Главные авторы: Lewis, Jared C., Bergman, Robert G., Ellman, Jonathan A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518126/
https://ncbi.nlm.nih.gov/pubmed/17411050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja070388z
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