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de novo Sequencing and Disulfide Mapping of a Bromotryptophan-Containing Conotoxin by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

T-1-family conotoxins belong to the T-superfamily and are composed of 10−17 amino acids. They share a common cysteine framework and disulfide connectivity, and exhibit unusual posttranslational modifications, such as tryptophan bromination, glutamic acid carboxylation and threonine glycosylation. We...

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Detalhes bibliográficos
Main Authors: Nair, Sudarslal Sadasivan, Nilsson, Carol L., Emmett, Mark R., Schaub, Tanner M., Gowd, Konkallu Hanumae, Thakur, Suman S., Krishnan, K. S., Balaram, Padmanabhan, Marshall, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518043/
https://ncbi.nlm.nih.gov/pubmed/17134143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac0607764
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