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Conformationally-Restricted Dipeptide Amides as Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors
Four new conformationally-restricted analogues of the potent and selective neuronal nitric oxide synthase inhibitor, L-nitroargininyl-L-2,4-diaminobutyramide (1), have been synthesized. N(α)-Methyl and N(α)-benzyl derivatives (3 and 4, respectively) of 4N-(L-Arg(NO(2)))-trans-4-amino-L-prolineamide...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517862/ https://ncbi.nlm.nih.gov/pubmed/17034131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0604124 |
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