Vascular endothelial growth factor overproduced by tumour cells acts predominantly as a potent angiogenic factor contributing to malignant progression

To elucidate the role of vascular endothelial growth factor (VEGF), an endothelial cell-specific mitogen, in tumour angiogenesis and malignant progression, an expression vector harboring human VEGF cDNA was stably transfected into three human cancer cell lines with poor VEGF productivity. Though the...

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Detalhes bibliográficos
Main Authors: Aonuma, Masashi, Saeki, Yoshiyuki, Akimoto, Toshihiko, Nakayama, Yutaka, Hattori, Chiharu, Yoshitake, Yoshino, Nishikawa, Katsuzo, Shibuya, Masabumi, Tanaka, Noriko G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517834/
https://ncbi.nlm.nih.gov/pubmed/10607018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2613.1999.00122.x
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