Eps15 Is Recruited to the Plasma Membrane upon Epidermal Growth Factor Receptor Activation and Localizes to Components of the Endocytic Pathway during Receptor Internalization

Eps15 is a substrate for the tyrosine kinase of the epidermal growth factor receptor (EGFR) and is characterized by the presence of a novel protein:protein interaction domain, the EH domain. Eps15 also stably binds the clathrin adaptor protein complex AP-2. Previous work demonstrated an essential ro...

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Hlavní autoři: Torrisi, Maria Rosaria, Lotti, Lavinia Vittoria, Belleudi, Francesca, Gradini, Roberto, Salcini, Anna Elisabetta, Confalonieri, Stefano, Pelicci, Pier Giuseppe, Di Fiore, Pier Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 1999
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC25178/
https://ncbi.nlm.nih.gov/pubmed/9950686
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