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Eps15 Is Recruited to the Plasma Membrane upon Epidermal Growth Factor Receptor Activation and Localizes to Components of the Endocytic Pathway during Receptor Internalization

Eps15 is a substrate for the tyrosine kinase of the epidermal growth factor receptor (EGFR) and is characterized by the presence of a novel protein:protein interaction domain, the EH domain. Eps15 also stably binds the clathrin adaptor protein complex AP-2. Previous work demonstrated an essential ro...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Torrisi, Maria Rosaria, Lotti, Lavinia Vittoria, Belleudi, Francesca, Gradini, Roberto, Salcini, Anna Elisabetta, Confalonieri, Stefano, Pelicci, Pier Giuseppe, Di Fiore, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25178/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9950686/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.2.417
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