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DNA Double-Strand Breaks: A Potential Causative Factor for Mammalian Aging?

Aging is a pleiotropic and stochastic process influenced by both genetics and environment. As a result the fundamental underlying causes of aging are controversial and likely diverse. Genome maintenance and in particular the repair of DNA damage is critical to ensure longevity needed for reproductio...

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Detalhes bibliográficos
Main Authors: Han, Li, Mitchell, James R., Hasty, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517577/
https://ncbi.nlm.nih.gov/pubmed/18346777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2008.02.002
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