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Pathogenesis of axonal dystrophy and demyelination in αA-crystallin-expressing transgenic mice

We recently described a transgenic mouse strain overexpressing hamster αA-crystallin, a small heat shock protein, under direction of the hamster vimentin promoter. As a result myelin was degraded and axonal dystrophy in both central nervous system (especially spinal cord) and peripheral nervous syst...

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Hlavní autoři: Van Rijk, AF, Sweers, MAM, Merkx, GFM, Lammens, M, Bloemendal, H
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517547/
https://ncbi.nlm.nih.gov/pubmed/12801283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2613.2003.00340.x
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