MCP-1/CCR2 signalling pathway regulates hyperoxia-induced acute lung injury via nitric oxide production

To clarify the role of the monocyte chemoattractant protein-1 (MCP-1)/C–C chemokine receptor 2 (CCR2) signalling pathway in hyperoxia-induced acute lung injury, CCR2-deficient (CCR2−/−) and wild-type (CCR2+/+) mice were exposed to 85% O(2) for up to 6 days. At day 3, body weight significantly decrea...

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Detalhes bibliográficos
Main Authors: Okuma, Toshiyuki, Terasaki, Yasuhiro, Sakashita, Naomi, Kaikita, Koichi, Kobayashi, Hironori, Hayasaki, Takanori, Kuziel, William A, Baba, Hideo, Takeya, Motohiro
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517387/
https://ncbi.nlm.nih.gov/pubmed/17222215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2006.00502.x
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