Blockade of CCR2 Ameliorates Progressive Fibrosis in Kidney

Fibrosis is a hallmark of progressive organ diseases. Monocyte chemoattractant protein (MCP)-1, also termed as macrophage chemotactic and activating factor (MCAF/CCL2) and its receptor, CCR2 are presumed to contribute to progressive fibrosis. However, the therapeutic efficacy of MCP-1/CCR2 blockade...

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Autors principals: Kitagawa, Kiyoki, Wada, Takashi, Furuichi, Kengo, Hashimoto, Hiroyuki, Ishiwata, Yoshiro, Asano, Masahide, Takeya, Motohiro, Kuziel, William A., Matsushima, Kouji, Mukaida, Naofumi, Yokoyama, Hitoshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2004
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618531/
https://ncbi.nlm.nih.gov/pubmed/15215179
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