Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC

Mlh1-knockout mice have been developed as a useful model of hereditary non-polyposis colorectal cancer (HNPCC). In this study, we analyzed the pathology of gastrointestinal tumours (GIT) in these mice in detail and examined the possible effects of ionizing radiation on the induction of intestinal tu...

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Main Authors: Tokairin, Yutaka, Kakinuma, Shizuko, Arai, Masami, Nishimura, Mayumi, Okamoto, Mieko, Ito, Eisaku, Akashi, Makoto, Miki, Yoshio, Kawano, Tatsuyuki, Iwai, Takehisa, Shimada, Yoshiya
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2006
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517356/
https://ncbi.nlm.nih.gov/pubmed/16623753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0959-9673.2006.00464.x
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