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Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC

Mlh1-knockout mice have been developed as a useful model of hereditary non-polyposis colorectal cancer (HNPCC). In this study, we analyzed the pathology of gastrointestinal tumours (GIT) in these mice in detail and examined the possible effects of ionizing radiation on the induction of intestinal tu...

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Détails bibliographiques
Auteurs principaux: Tokairin, Yutaka, Kakinuma, Shizuko, Arai, Masami, Nishimura, Mayumi, Okamoto, Mieko, Ito, Eisaku, Akashi, Makoto, Miki, Yoshio, Kawano, Tatsuyuki, Iwai, Takehisa, Shimada, Yoshiya
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2006
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517356/
https://ncbi.nlm.nih.gov/pubmed/16623753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0959-9673.2006.00464.x
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