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Complex genetic predisposition to cancer in an extended HNPCC family with an ancestral hMLH1 mutation.

Hereditary non-polyposis colorectal cancer (HNPCC) is characterised by a genetic predisposition to develop colorectal cancer at an early age and, to a lesser degree, cancer of the endometrium, ovaries, urinary tract, and organs of the gastrointestinal tract other than the colon. In the majority of f...

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Détails bibliographiques
Auteurs principaux: Hutter, P, Couturier, A, Scott, R J, Alday, P, Delozier-Blanchet, C, Cachat, F, Antonarakis, S E, Joris, F, Gaudin, M, D'Amato, L, Buerstedde, J M
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050695/
https://ncbi.nlm.nih.gov/pubmed/8863153
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