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Selective lesion of retrotrapezoid Phox2b-expressing neurons raises the apnoeic threshold in rats
Injection of the neurotoxin saporin–substance P (SSP-SAP) into the retrotrapezoid nucleus (RTN) attenuates the central chemoreflex in rats. Here we ask whether these deficits are caused by the destruction of a specific type of interneuron that expresses the transcription factor Phox2b and is non-cat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517201/ https://ncbi.nlm.nih.gov/pubmed/18440993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.153163 |
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