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Asymmetric nucleotide transactions of the HslUV protease
ATP binding and hydrolysis are critical for protein degradation by HslUV, a AAA+ machine containing one or two HslU(6) ATPases and the HslV(12) peptidase. Although each HslU homohexamer has six potential ATP-binding sites, we show that only three or four ATP molecules bind at saturation and present...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517146/ https://ncbi.nlm.nih.gov/pubmed/18582897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.070 |
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