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Pre-Steady State Studies of Phosphite Dehydrogenase Demonstrate that Hydride Transfer is Fully Rate-Limiting

Phosphite dehydrogenase (PTDH) is a unique NAD-dependent enzyme that catalyzes the oxidation of inorganic phosphite to phosphate. The enzyme has great potential for cofactor regeneration and mechanistic studies have provided some insight into the residues that are important for catalysis. In this in...

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Bibliografische gegevens
Hoofdauteurs: Fogle, Emily J., van der Donk, Wilfred A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517116/
https://ncbi.nlm.nih.gov/pubmed/17949110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701550c
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