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Proteasome Activation by Hepatitis C Core Protein is Reversed by Ethanol-Induced Oxidative Stress: Proreasome activation by HCV core protein

BACKGROUND AND AIMS: The proteasome is a major cellular proteinase. Its activity is modulated by cellular oxidants. Hepatitis C core protein and ethanol exposure both cause enhanced oxidant generation. The aim was to investigate whether core protein, by its ability to generate oxidants, alters prote...

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Библиографические подробности
Главные авторы: Osna, Natalia A., White, Ronda L., Krutik, Viatcheslav M., Wang, Ting, Weinman, Steven A., Donohue, Terrence M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517112/
https://ncbi.nlm.nih.gov/pubmed/18549882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.02.063
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