Mechanistic Studies on ADAMTS13 Catalysis

The zinc-protease a disintegrin-like and metalloprotease with thrombospondin type I repeats (ADAMTS13) cleaves the Tyr(1605)-Met(1606) peptide bond of von Willebrand factor (VWF), avoiding the accumulation of ultra large VWF multimers. Hydrolysis by ADAMTS13 of a VWF analog (Asp(1596)-Arg(1668) pept...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Di Stasio, Enrico, Lancellotti, Stefano, Peyvandi, Flora, Palla, Roberta, Mannucci, Pier Mannuccio, De Cristofaro, Raimondo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2008
Pynciau:
Proteins
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517044/
https://ncbi.nlm.nih.gov/pubmed/18502798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.131532
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