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T7 RNA Polymerase Studied by Force Measurements Varying Cofactor Concentration

RNA polymerases carry out the synthesis of an RNA copy from a DNA template. They move along DNA, incorporate nucleotide triphosphate (NTP) at the end of the growing RNA chain, and consume chemical energy. In a single-molecule assay using the T7 RNA polymerase, we study how a mechanical force opposin...

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Main Authors: Thomen, P., Lopez, P. J., Bockelmann, U., Guillerez, J., Dreyfus, M., Heslot, F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517023/
https://ncbi.nlm.nih.gov/pubmed/18708471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.125096
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