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T7 RNA Polymerase Studied by Force Measurements Varying Cofactor Concentration
RNA polymerases carry out the synthesis of an RNA copy from a DNA template. They move along DNA, incorporate nucleotide triphosphate (NTP) at the end of the growing RNA chain, and consume chemical energy. In a single-molecule assay using the T7 RNA polymerase, we study how a mechanical force opposin...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517023/ https://ncbi.nlm.nih.gov/pubmed/18708471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.125096 |
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