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A mutation in T7 RNA polymerase that facilitates promoter clearance
Like multisubunit RNA polymerases (RNAPs), T7 RNAP frequently releases its transcript over the initial 8-12 transcribed nucleotides, when it still contacts the promoter. This abortive cycling, which is most prominent with initial sequences that deviate from those of T7 late genes, eventually comprom...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087904/ https://ncbi.nlm.nih.gov/pubmed/15831591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407141102 |
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