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The Bound States of Amphipathic Drugs in Lipid Bilayers: Study of Curcumin

Drug-membrane interactions are well known but poorly understood. Here we describe dual measurements of membrane thickness change and membrane area change due to the binding of the amphipathic drug curcumin. The combined results allowed us to analyze the binding states of a drug to lipid bilayers, on...

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書誌詳細
主要な著者: Sun, Yen, Lee, Chang-Chun, Hung, Wei-Chin, Chen, Fang-Yu, Lee, Ming-Tao, Huang, Huey W.
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517021/
https://ncbi.nlm.nih.gov/pubmed/18515370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.133736
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