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The Bound States of Amphipathic Drugs in Lipid Bilayers: Study of Curcumin

Drug-membrane interactions are well known but poorly understood. Here we describe dual measurements of membrane thickness change and membrane area change due to the binding of the amphipathic drug curcumin. The combined results allowed us to analyze the binding states of a drug to lipid bilayers, on...

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Detalhes bibliográficos
Main Authors: Sun, Yen, Lee, Chang-Chun, Hung, Wei-Chin, Chen, Fang-Yu, Lee, Ming-Tao, Huang, Huey W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517021/
https://ncbi.nlm.nih.gov/pubmed/18515370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.133736
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