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A Simulation Study on the Activation of Cardiac CaMKII δ-Isoform and Its Regulation by Phosphatases

Although the highly conserved Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is known to play an essential role in cardiac myocytes, its involvement in the frequency-dependent acceleration of relaxation is still controversial. To investigate the functional significance of CaMKII autophosphor...

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Main Authors: Chiba, Hiroaki, Schneider, Natalie S., Matsuoka, Satoshi, Noma, Akinori
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517018/
https://ncbi.nlm.nih.gov/pubmed/18502812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.118505
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