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Directed Hydrozirconation of Homopropargylic Alcohols

Homopropargylic alcohols undergo directed hydrozirconation with Schwartz reagent (Cp(2)ZrHCl) to generate vinyl-metal species in which the metal fragment is proximal to the alkoxide. Electrophilic trapping yields tri-substituted olefins in good yields with good control of regio- and stereochemistry....

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Détails bibliographiques
Auteurs principaux: Liu, Xiaofeng, Ready, Joseph M.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516920/
https://ncbi.nlm.nih.gov/pubmed/19122870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.03.052
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