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Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones

The homotypic fusion of yeast vacuoles, each with 3Q- and 1R-SNARE, requires SNARE chaperones (Sec17p/Sec18p and HOPS) and regulatory lipids (sterol, diacylglycerol and phosphoinositides). Pairs of liposomes of phosphatidylcholine/phosphatidylserine, bearing three vacuolar Q-SNAREs on one and the R-...

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Detalhes bibliográficos
Main Authors: Mima, Joji, Hickey, Christopher M, Xu, Hao, Jun, Youngsoo, Wickner, William
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516887/
https://ncbi.nlm.nih.gov/pubmed/18650938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.139
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