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Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin
BACKGROUND: Bowing and/or pseudarthrosis of the tibia is a known severe complication of neurofibromatosis type 1 (NF1). Mice with conditionally inactivated neurofibromin (Nf1) in the developing limbs and cranium (Nf1Prx1) show bowing of the tibia caused by decreased bone mineralisation and increased...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516519/ https://ncbi.nlm.nih.gov/pubmed/18671844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-6-21 |
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